Role of the human V[sub 1] vasopressin receptor COOH terminus in internalization and mitogenic signal transduction.
- Resource Type
- Article
- Authors
- Thibonnier, Marc; Plesnicher, Christine L.; Berrada, Karim; Berti-Mattera, Liliana
- Source
- American Journal of Physiology: Endocrinology & Metabolism. Jul2001, Vol. 44 Issue 1, pE81. 12p. 1 Diagram, 2 Charts, 4 Graphs.
- Subject
- *ARGININE
*PHYSIOLOGICAL control systems
*CELLULAR signal transduction
- Language
- ISSN
- 0193-1849
Studies the role played by intracellular COOH-terminal region of the human arginine vasopressin vascular (AVP) receptor in ligand binding, transport and mitogenic transduction in Chinese hamster ovary cells. Reagents used; Details on receptor constructs; Findings on the radioligand binding characteristics of the mutated AVP receptors.