Accuracy of a semi-quantitative urine pregnancy test compared to serum beta-hCG measurement: a possible screening tool for ongoing pregnancy after medication abortion
- Resource Type
- Article
- Authors
- Grossman, Daniel; Berdichevsky, Karla; Larrea, Fernando; Beltran, Jorge
- Source
- Contraception. Aug2007, Vol. 76 Issue 2, p101-104. 4p.
- Subject
- *PREGNANCY
*ABORTION
*SERUM
*URINALYSIS
- Language
- ISSN
- 0010-7824
Abstract: Purpose: Medication abortion protocols commonly rely on ultrasound or serum hCG measurement to confirm completion. In order to explore the use of a urine-based test to screen for ongoing pregnancy, we compared the diagnostic accuracy of a recently developed semi-quantitative urine pregnancy test to serum β-hCG testing. Methods: We evaluated the urine test with 97 women in early pregnancy at a hospital and private clinic in Mexico City. The results of the urine test (hCG level > or <1000 IU/L) were correlated with those of a serum quantitative β-hCG immunoradiometric assay. Results: The sensitivity of the urine test to identify individuals with a serum β-hCG level >1000 IU/L was 88.6% (95% CI 74.6– 95.7%), and its specificity was 71.7% (95% CI 57.4–82.8%). Conclusion: The reasonably high sensitivity of this urine test suggests it might be useful as a screening test to detect ongoing pregnancy after medication abortion. Future research should evaluate its utility in clinical follow-up protocols. [Copyright &y& Elsevier]