Objective: Renal colic is a commonly encountered clinical presentation. Our objective is to evaluate the accurate diagnostic yield of low-dose CT KUB for the detection of urinary calculi, to minimize radiation dose to the patients, and to analyze the diagnostic accuracy of low-dose CT KUB when compared to regular dose CT KUB. We speculate the low dose CT-KUB may reduce patient radiation dose while maintaining diagnostic value. Materials and Methods: This comparative cross-sectional validation study was conducted at the Department of Radiology in Benazir Bhutto Hospital, Rawalpindi June 2021 to Feb 2022. After approval of the hospital's ethical committee, a sample of 49 kidneys of 31 patients was collected by non-probability consecutive sampling technique. Included were the patients diagnosed with renal calculi referred from other departments. All the included patients were scanned by Toshiba Aquilion 16 slices, using automated tube current modulation, without any oral or IV contrast. CT scan started from the diaphragm down to pubic symphysis with standard-dose CT (SDCT) followed by low-dose CT (LDCT). After the data was recorded, a statistical package for social sciences, version 20.0 (SPSS Inc., Chicago, Illinois, USA) was used to analyse the data and generate results. Mean + standard deviation was calculated for qualitative data while frequency and percentage for qualitative variables. The means were compared by independent sample t-test while the agreement between standard and low dose was depicted by kappa value. Results: A total number of 49 kidneys of 31 persons having renal stones was added to the study. The mean age of the included patients ranges from years 27 to years 48 with a mean age of years 36.42 + 9.97. In gender distribution, 75.5 % (37) were male while 24.5 % (12) were females. More than half 59 % (29) were right while 41 % (20) were left kidneys. Conclusion: Our study demonstrated that LOW DOSE CT KUB was a productive and efficient modality in the diagnosis of urothelial stones despite considerably reduced radiation dose and exposure as seen in standard dose CT KUB. [ABSTRACT FROM AUTHOR]