Keywords: Primary immunodeficiency; combined immunodeficiency diseases; molecular genetics; autosomal recessive; infection; renal; Gitelman syndrome; NGS; MST1 The clinical and immunological presentation for CID due to STK4 mutation is variable and our patient had some of the common features reported previously such as recurrent viral skin infection, autoimmune cytopenia, congenital heart diseases, and hypergammaglobulinemia [[3], [5]]. Primary immunodeficiency, combined immunodeficiency diseases, molecular genetics, autosomal recessive, infection, renal, Gitelman syndrome, NGS, MST1. [Extracted from the article]