Syndrome in Question
- Resource Type
- report
- Authors
- MA, Han; Chen, Meilan; Li, Juan; Li, Ying; Qiu, Shu
- Source
- Anais Brasileiros de Dermatologia. April 2015 90(2)
- Subject
- Amyloidosis
Scleroderma, diffuse
Skin manifestations
- Language
- English
- ISSN
- 0365-0596
Immunoglobulin light chain amyloidosis is the most common acquired systemic amyloidosis. Its presentation is often insidious and progressive, which may delay diagnosis. The authors describe a rare case of immunoglobulin light chain amyloidosis in a 34-year-old man with scleroderma-like manifestation substantiated by multifarious laboratory investigations and the histopathologic feature of involved skin lesions stained with Congo red and crystal violet. This helps to maintain a high clinical suspicion of the disease when confronting similar skin presentation.