This paper mainly studies the piezoelectric driving amplifier for the trailing edge flaps of wind turbine blades. Firstly, two kinds of structure models of piezoelectric amplifier are built by using three-dimensional software, and then ANSYS analysis software is imported. Then, the analysis module is built on the working platform. Secondly, material parameters are input and meshing is done. In order to ensure the quality, we choose high-order quadrilateral element to refine the local mesh in order to improve the accuracy. At the same time, restrictions and pressures should be imposed. Finally, the simulation results are analyzed, and the diamond amplifier is selected as the comparison analysis result, which provides a reference for the application of piezoelectric driving mechanism in intelligent wind turbine blades.