The presence of delirium and its sequelae in critically ill pediatric patients is increasingly being recognized. Validated bedside screening tools nurses use have emerged to assist pediatric providers in the early identification of delirium. Nurses' compliance and scoring accuracy of delirium screening tools have improved following education and an increased understanding of delirium. The aims of this project were to increase nurses' knowledge of pediatric delirium and implement twice-daily delirium screening using the Cornell Assessment of Pediatric Delirium (CAPD) screening tool in a community-based pediatric intensive care unit (PICU). Nursing knowledge was evaluated using a pre-/post-survey of pediatric delirium following a didactic delirium lecture and case study activity. Following the implementation of the CAPD tool into the electronic health record (EHR), twice-daily delirium screening was implemented and measured for screening compliance. Nursing knowledge decreased between the two measurement periods, although not significantly. Complete delirium screens, defined as screening occurring after the first ICU day, on non-sedated or lightly sedated patients at the end of the nursing shift occurred in 60% of scoring opportunities. [ABSTRACT FROM AUTHOR]