Risk and Prognosis of Second Primary Cancers among Ovarian Cancer Patients, Based on SEER Database.
- Resource Type
- Article
- Authors
- Wang, Qi; Liu, Tianyu; Liu, Chang; Wang, Wanyu; Zhai, Jiabao; Han, Xu; Nie, Chuang; Ren, Xiyun; Zhu, Xioajie; Xiang, Guanghui; Zhou, Haibo; Tian, Wenjing; Li, Xiaomei
- Source
- Cancer Investigation. Aug2022, Vol. 40 Issue 7, p604-620. 17p.
- Subject
- *STATISTICS
*REPORTING of diseases
*OVARIAN tumors
*PREDICTIVE tests
*CANCER patients
*SECONDARY primary cancer
*SURVIVAL analysis (Biometry)
*STATISTICAL models
*DATA analysis
*PROBABILITY theory
*DISEASE risk factors
- Language
- ISSN
- 0735-7907
The purposes of the present study were to elucidate the risk and prognostic effect of second primary cancers (SPCs) development, as well as the factors influencing the prognosis of OC patients with SPCs. A statistically significant increase in SPCs risk was observed among OC patients during 2004–2015. The independent factors were used to construct the SPCs-prediction nomogram and the OS-prediction nomogram. Both nomogram were subjected to internal validation and performed well. OC patients with SPCs have a better prognosis than patients without SPCs. Propensity score matching (PSM) was applied to reduce confounding. [ABSTRACT FROM AUTHOR]