In summary, PPOIT induced desensitization in 75% (16/20) and 8-week SU in 60% (12/20) of patients, with SU persisting at 3-year post-treatment after I ad libitum i peanut ingestion in 50% (6/12) of initial treatment responders. Importantly, PPOIT was associated with a substantial HRQL improvement by 12-month post-treatment that was sustained at 3-year post-treatment. Keywords: health-related quality of life; oral immunotherapy; Peanut allergy; probiotic and peanut oral immunotherapy; sustained unresponsiveness EN health-related quality of life oral immunotherapy Peanut allergy probiotic and peanut oral immunotherapy sustained unresponsiveness 806 811 6 06/01/22 20220601 NES 220601 Key message There are few data on long-term effects and quality-of-life impact of peanut OIT. At T5, 6 (50%) of the 12 subjects who initially achieved SU at 8-week post-treatment still had persistent 8-week SU after 3 years of I ad libitum i intake at 3-year post-treatment. [Extracted from the article]