Reliability and diagnostic accuracy of corrected slack angle derived from 2D-SWE in quantitating muscle spasticity of stroke patients.
- Resource Type
- Article
- Authors
- Cao, Junyan; Xiao, Yang; Qiu, Weihong; Zhang, Yanling; Dou, Zulin; Ren, Jie; Zheng, Rongqin; Zheng, Hairong; Chen, Zhaocong
- Source
- Journal of NeuroEngineering & Rehabilitation (JNER). 2/5/2022, Vol. 19 Issue 1, p1-11. 11p.
- Subject
- *SPASTICITY
*STROKE patients
*RECEIVER operating characteristic curves
*BOTULINUM toxin
*BOTULINUM A toxins
- Language
- ISSN
- 1743-0003
Background: To explore the feasibility of corrected slack angle acquired from two-dimensional shear wave elastography (2D-SWE) for quantitating the spasticity of medial gastrocnemius (MG) in stroke patients. Methods: Consecutive stroke patients with spastic MG and matched healthy controls were recruited. Intra- and interobserver reliability of 2D-SWE measurement were evaluated, and the correlation between corrected slack angle and modified Ashworth scale (MAS) score was examined. The corrected slack angle before and after botulinum toxin A (BoNT-A) injection was compared and its diagnostic performance in classifying the severity of spasticity were assessed with receiver operating characteristic (ROC) curve analysis. Results: The intra- (0.791 95% CI 0.432–0.932) and interobserver (0.751 95% CI 0.382–0.916) reliability of slack angle acquired with 2D-SWE were good. Significant correlation was found between corrected slack angle and MAS score (R = − 0.849, p < 0.001). The corrected slack angle increased after BoNT-A injection. The cutoff value of MAS ≥ 3 had the highest sensitivity (100%) and specificity (93.33%). The positive predictive value (PPV) for classification of MAS ≥ 1+ and the negative predictive value (NPV) for classification of MAS ≥ 3 were greater than 90%. Conclusion: 2D-SWE was a reliable method to quantitate the post-stroke spasticity. The corrected slack angle had advantage in classifying the severity of spasticity, especially in early identification of mild spasticity and confirmation of severe spasticity. [ABSTRACT FROM AUTHOR]