Visible-Light-Promoted Indole C-3 Formylation Using Eosin Y as a Photoredox Catalyst.
- Resource Type
- Article
- Authors
- Zhao, Yin; Li, Hongfang; Yin, Shan; Wu, Yandan; Ni, Guanghui
- Source
- Synlett. Apr2022, Vol. 33 Issue 7, p659-663. 5p.
- Subject
- *FORMYLATION
*INDOLE
*EOSIN
*FUNCTIONAL groups
*CATALYSTS
*INDOLE compounds
- Language
- ISSN
- 0936-5214
A visible-light-mediated C-3 formylation of indole catalyzed by eosin Y has been developed using tetramethylethylenediamine as a carbon source and air as an oxidant. This protocol shows high tolerance to a large quantity of functional groups under mild conditions and provides 3-formylated indoles with good yields. This method is a highly attractive alternative to the approach of traditional formylation. [ABSTRACT FROM AUTHOR]