This work presents the comparative study among pole-placement (PP), optimalcontrol using output-feedback (OCOF), linear-quadratic regulator (LQR), and PID controllers for the twin rotor multi-input multi-output system (TRMS). The pitch and yaw are key attributes for stabilizing the TRMS MIMO system and control of flight. The main objective of this study is to use these classical controller techniques to monitor the pitch and yaw angles of TRMS and show the result of these techniques. Simulation results depicts the actual performance and reveals how PP outperforms the other techniques.