One of the complications of indwelling central venous catheters is the difficulty in their removal. We experienced treating a case in which the catheter was last replaced at the age of 15 years for nutritional management and was left in place from the left internal jugular vein to the superior vena cava at the age of 23 years owing to difficulty in its removal. The duration in which the last catheter was left in place was 14 years and 8 months. The patient died at the age of 30 years owing to a worsening respiratory condition caused by infection and progressive prerenal renal failure associated with gastrointestinal bleeding. Pathological autopsy revealed scar tissue surrounding the catheter, and foreign bodies scattered in the scar tissue. In addition, there was fibrous stenosis or occlusion in the peripheral pulmonary artery, and foreign bodies were found inside the peripheral pulmonary artery. Our experience suggests that parts of the catheter might spontaneously detach and scatter as foreign bodies as time passes. In patients who can survive for a long time, catheter removal, including via open-heart surgery, should be considered.