Leukemia, a malignant blood cancer, is characterized by the uncontrolled proliferation of abnormal white blood cells in the bone marrow and blood. It is a life-threatening disease with various subtypes, making precise classification crucial for effective treatment. However, accurate classification of leukemia subtypes from abnormal cell images poses a challenging problem due to the complex and subtle variations in cell morphology. In response to this challenge, this comprehensive study employs an innovative machine learning approach, utilizing the EfficientNet B3 architecture. With this model, we achieved an impressive accuracy rate of 98.95% and a minimal loss of 0.120, demonstrating its efficacy in classifying leukemia subtypes. To conduct our experiments, we utilized the Kaggle Leukemia cancer dataset, ensuring a robust and reliable evaluation of our proposed methodology. This research contributes significantly to the development of efficient tools for early diagnosis and personalized treatment strategies for leukemia.