Background: India has one of the largest health-care systems in the world, and caregivers play an important role in assisting the patients in seeking services, supporting the patient during treatment and also in recovery, as there is a culturally determined emphasis on kinship obligations, with families playing a prominent role in all decisions regarding treatment. The burden this places on the caregiver can undermine their physical, psychological, and functional health. There is a paucity of studies examining caregiver burden in relation to type caregivers (formal or informal) and type of wards (general or special). Our study aims to explore whether their burden and coping differ in relation to the type of ward services. Aims: The aim of the study was (i) to compare the burden among caregivers of general ward patients with that of special ward patients and (ii) to study the satisfaction of hospital services by caregivers in general ward versus special wards. Methods: Sixty caregivers each of general ward and special ward patients were assessed. The caregiver burden scale was utilized to appraise burden, and their coping was evaluated with the revised caregiver efficacy scale. Results:Caregiver burden was more for special wards compared to general wards. Caregiver self-efficacy was more among the primary caregivers of general ward patients. Conclusions:Caregiver burden and self-efficacy play an important role in satisfaction with the service quality of the health-care organization. Education about various aspects of caregiving and early identification of burden areas should be done to allow optimal management strategies tailored for the individual patient and caregiver.