When two Z-scores meet—analysis of exercise capacity of children and adolescents with Kawasaki disease by a new Z-score model of coronary artery and a new Z-score evaluating peak oxygen consumption
- Resource Type
- article
- Authors
- Sheng-Hui Tuan; Jin-Hui Chung; Guan-Bo Chen; Shu-Fen Sun; I-Hsiu Liou; Chien-Hui Li; Yi-Ju Tsai
- Source
- Italian Journal of Pediatrics, Vol 49, Iss 1, Pp 1-10 (2023)
- Subject
- Cardiopulmonary exercise testing
Coronary artery Z score
Exercise capacity
Kawasaki disease
Peak oxygen consumption
Pediatrics
RJ1-570
- Language
- English
- ISSN
- 1824-7288
Abstract Background Coronary artery (CA) Z-score system is widely used to define CA aneurysm (CAA). Children and adolescents after acute stage of Kawasaki disease (KD-CA) have a higher risk of developing CAAs if their CA Z-score ≥ 2.5. Z-score system of peak oxygen consumption (Peak VO2 Z-score) allows comparisons across ages and sex, regardless of body size and puberty. We aimed to compare the exercise capacity (EC) indicated by peak VO2 Z-score during cardiopulmonary exercise testing (CPET) directly between KD-CA with different CA Z-score. Methods KD-CA after acute stage who received CPET in the last 5 years were retrospectively recruited. CA Z-score was based on Lambda-Mu-Sigma method. Max-Z was the maximum CA Z-score of different CAs. KD children with Max-Z