High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM
- Resource Type
- article
- Authors
- Mark A. Herzik; Mengyu Wu; Gabriel C. Lander
- Source
- Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
- Subject
- Science
- Language
- English
- ISSN
- 2041-1723
Despite many recent advances in cryo-EM, imaging smaller macromolecules (below 100 kDa) has remained a challenge. Here the authors show that biological specimens amassing