HETEROCYCLIZATION USING PHASE TRANSFER CATALYSIS: A SIMPLE AND CONVENIENT SYNTHESIS OF 2-AMINO-1-ARYL-5-OXO-4,5-DIHYDRO-1H-PYRROLE-3-CARBONITRILES
- Resource Type
- Authors
- Vaishali A. Parikh; Chaitanya G. Dave
- Source
- Synthetic Communications. 31:1301-1306
- Subject
- chemistry.chemical_compound
chemistry
Simple (abstract algebra)
Aryl
Phase (matter)
Organic Chemistry
Acetonitrile
Combinatorial chemistry
Pyrrole
Catalysis
- Language
- ISSN
- 1532-2432
0039-7911
A simple and convenient synthesis of 2-amino-1-aryl-5-oxo-4,5-dihydro-1H-pyrrole-3-carbonitriles has been studied with and without phase transfer conditions. The best results were obtained using 18-crown-6 under solid-liquid phase transfer conditions in acetonitrile.