Additional file 2: Figure S1. Quantitative validation of miR-29a knockdown in MDA-MB-231 (A) and MCF-10A-SRC (B) cells. Figure S2. Overexpression of miR-29a promoted cell migration and invasion, and induced EMT in MDA-MB-231 cells. Figure S3. Overexpression of miR-29a promoted cell migration and invasion, and induced EMT in MCF-10A-SRC cells. Figure S4. Quantitative validation of miR-29a overexpression in MCF-7 cells. Figure S5. Image and weight of the mammary tumors derived from mice transplanted with MCF-10A-SRC cells with or without overexpression of miR-29a. Figure S6. Higher levels of PTEN in ERα+ breast cancer tumors (n=808) than that in ERα- ones (n=238). Figure S7. Correlations between miR-29a, PTEN and ERα in different stages of breast cancer patients. Figure S8. Image and weight of the mammary tumors from the mice treated with miR-29a inhibitor or control.