Observed Sex Differences in Cardiometabolic Indices in Patients on Antipsychotics: Secondary Analyses of a 12-Month Multicenter, Randomized, Controlled Trial
- Resource Type
- Authors
- Xuan Li; Mark E. Schneiderhan
- Source
- The primary care companion for CNS disorders. 23(2)
- Subject
- Male
medicine.medical_specialty
Waist
Pharmacist
Blood Pressure
law.invention
chemistry.chemical_compound
Patient satisfaction
Randomized controlled trial
law
Internal medicine
medicine
Humans
Response rate (survey)
Glycated Hemoglobin
Sex Characteristics
business.industry
General Medicine
medicine.disease
Blood pressure
chemistry
Hypertension
Female
Glycated hemoglobin
business
Dyslipidemia
Antipsychotic Agents
- Language
- ISSN
- 2155-7780
OBJECTIVE To define sex differences in cardiometabolic indice changes over 12 months in patients on antipsychotics and to describe treatment complexity, interventions, and patient satisfaction of pharmacist comprehensive medication management (CMM) services. METHODS Secondary analyses of time effect-associated sex differences in cardiometabolic indices within and between study groups were done at baseline and 12 months. Each group consisted of 60 subjects who received full pharmacist CMM services (PCS) and 60 subjects who received either modified or no CMM services (NCS). Pharmacist CMM services are a team-based practice of providing direct patient care. RESULTS Significant sex differences in mean change score were observed from baseline to 12 months in the combined PCS and NCS subjects. Compared to men, women had greater body weight (P = .003) and waist measurement (P = .02) reductions and increased serum level of high-density lipoproteins (P