Biexponential T
- Resource Type
- Authors
- Azadeh, Sharafi; Ding, Xia; Gregory, Chang; Ravinder R, Regatte
- Source
- NMR in biomedicine. 30(10)
- Subject
- musculoskeletal diseases
Adult
Cartilage, Articular
Male
Reproducibility of Results
musculoskeletal system
Magnetic Resonance Imaging
Article
Image Processing, Computer-Assisted
Animals
Humans
Cattle
Computer Simulation
Female
Knee
Monte Carlo Method
- Language
- ISSN
- 1099-1492
In this study, we demonstrated the feasibility of in-vivo biexponential T1ρ relaxation mapping of knee articular cartilage of 8 healthy volunteers using 3T MRI in clinically feasible scan times. Our preliminary results show that the biexponential model may better represents the T1ρ relaxation decay in articular cartilage. It is possible distinguish between tightly bound and loosely bound water compartments associated with macromolecules in the articular cartilage.