Supplementary Tables S1-3. Table S1. IC25/50/75 and LC50 values of AT7519 for MYCN-amplified and non-MYCN-amplified neuroblastoma cell lines and cell seeding densities used to perform MTT cell proliferation assays (96-well plates). IC25/50/75 and LC50 values are derived from dose-response curves. Table S2. In vitro effects on sub-G1 induction and cell cycle progression in MYCN-amplified versus non-MYCN-amplified neuroblastoma cell lines after 72 h treatment with AT7519. Values represent the average percentage of cells in sub-G1, G1, S and G2 +/- SD. Table S3. Pharmacokinetic parameters derived from plasma disappearance and tumour accumulation curves after intraperitoneal administration of AT7519 to mice bearing MYCN-amplified AMC711T neuroblastoma xenografts.