2D Projection Analysis of GPCR Complexes by Negative Stain Electron Microscopy
- Resource Type
- Authors
- Alys Peisley; Georgios Skiniotis
- Source
- Methods in Molecular Biology ISBN: 9781493929139
- Subject
- Biological specimen
Membrane protein complex
law
Particle classification
Thin layer
Macromolecular Complexes
Biophysics
Biology
Electron microscope
Negative stain
law.invention
G protein-coupled receptor
- Language
While electron cryo-microscopy (cryo-EM) of biological specimens is the preferred single particle EM method for structure determination, its application is very challenging for the typically small (