Malignant Mixed Epithelial and Stromal Tumor of the Kidney With 2 Simultaneous Renal Carcinomas in a Male Patient: Case Report and Review of the Literature
- Resource Type
- Authors
- Aileen Grace P. Arriola; S. Bruce Malkowicz; Sophia Ma; Benjamin L Taylor; Priti Lal
- Source
- International journal of surgical pathology. 26(1)
- Subject
- 0301 basic medicine
Male
medicine.medical_specialty
Pathology
Stromal cell
medicine.medical_treatment
Cell
urologic and male genital diseases
Pathology and Forensic Medicine
Neoplasms, Multiple Primary
03 medical and health sciences
0302 clinical medicine
Medicine
Humans
Stromal tumor
Carcinoma, Renal Cell
Kidney
Incidental Findings
business.industry
Middle Aged
Neoplasms, Complex and Mixed
Nephrectomy
Kidney Neoplasms
030104 developmental biology
medicine.anatomical_structure
Male patient
030220 oncology & carcinogenesis
Surgery
Histopathology
Anatomy
business
Clear cell
- Language
- ISSN
- 1940-2465
The majority of mixed epithelial and stromal tumors (MEST) of the kidney are benign entities found in female patients. Malignant MEST of the kidney is an extremely rare entity that often behaves clinically similar to an undifferentiated sarcoma. We report a case of a malignant MEST with synchronous papillary and clear cell renal cell carcinomas (RCCs) in a 61-year-old Caucasian man who presented with an incidental finding of a left renal mass on workup for back pain. The patient underwent a left radical nephrectomy, with histopathology confirming a malignant MEST, intimately associated papillary RCC, and separate adjacent focus of clear cell RCC.