Multigene Sequencing Analysis of Children Born Small for Gestational Age With Isolated Short Stature.
- Resource Type
- Article
- Authors
- Freire, Bruna L; Homma, Thais K; Funari, Mariana F A; Lerario, Antônio M; Vasques, Gabriela A; Malaquias, Alexsandra C; Arnhold, Ivo J P; Jorge, Alexander A L
- Source
- The Journal of Clinical Endocrinology & Metabolism; June 2019, Vol. 104 Issue: 6 p2023-2030, 8p
- Subject
- Language
- ISSN
- 0021972X; 19457197
Patients born small for gestational age (SGA) who present with persistent short stature could have an underlying genetic etiology that will account for prenatal and postnatal growth impairment. We applied a unique massive parallel sequencing approach in cohort of patients with exclusively nonsyndromic SGA to simultaneously interrogate for clinically substantial genetic variants.