Andexanet alfa and heparin resistance in cardiac surgery: Experiences and risks associated with the reversal of direct oral anticoagulants.
- Resource Type
- Article
- Authors
- Dohle, Daniel-Sebastian; Pfeiffer, Philipp; Probst, Chris; Treede, Hendrik
- Source
- European Journal of Cardio-Thoracic Surgery. Jun2023, Vol. 63 Issue 6, p1-2. 2p.
- Subject
- *ORAL medication
*HEPARIN
*CARDIAC surgery
*AORTIC dissection
*ANTICOAGULANTS
*MECHANICAL hearts
- Language
- ISSN
- 1010-7940
Keywords: Andexanet alfa; direct oral anticoagulants; heart-lung machine; heparin resistance EN Andexanet alfa direct oral anticoagulants heart-lung machine heparin resistance 1 2 2 07/04/23 20230601 NES 230601 In their case report "Andexanet alfa in acute aortic syndrome: first UK experience", Al-Attar I et al. i describe their experiences with Andexanet alfa (AA) in the context of emergency surgeries for type A aortic dissections [[1]]. While the procedure was complication free and hemostasis was ensured in the 2 patients who received AA post-CPB, achieving suitable ACT despite repetitive heparin administrations in the patient with pre-hospital AA administration proved difficult. [Extracted from the article]