Peripheral group II and III metabotropic glutamate receptors in the knee joint attenuate carrageenan-induced nociceptive behavior in rats.
- Resource Type
- Article
- Authors
- Lee, Kyu Sang; Park, Eui Ho; Cho, Hwi-young; Kim, Yang In; Han, Hee Chul
- Source
- Neuroscience Letters. May2013, Vol. 542, p21-25. 5p.
- Subject
- *GLUTAMATE receptors
*CARRAGEENANS
*NOCICEPTIVE pain
*HYPERALGESIA
*LABORATORY rats
*KNEE abnormalities
- Language
- ISSN
- 0304-3940
Highlights: [•] We evaluated effects of peripheral group II and III mGluR on arthritic pain of rats. [•] Pain behavior is relevant with reduced weight bearing and mechanical hyperalgesia. [•] Pre-treatment of group II and III mGluR agonist attenuated nociceptive behavior. [•] Post-treatment of group II and III mGluR agonist attenuated nociceptive behavior. [ABSTRACT FROM AUTHOR]