Disseminated intravascular coagulation during liver transplantation unleashed by protamine.
- Resource Type
- case study
- Authors
- Raveh, Yehuda; Shatz, Vadim; Lindsay, Martine; Nicolau-Raducu, Ramona
- Source
- Journal of Clinical Anesthesia. Nov2019, Vol. 57, p117-118. 2p.
- Subject
- *DISSEMINATED intravascular coagulation
*LIVER transplantation
*HEPARIN
*VENOUS thrombosis diagnosis
*VENOUS thrombosis treatment
*HEPATOCELLULAR carcinoma
*CIRRHOSIS of the liver
*LIVER tumors
*PORTAL vein
*THROMBELASTOGRAPHY
*VENOUS thrombosis
*TREATMENT effectiveness
*PROTAMINES
*AMINOCAPROIC acids
*HEPARIN antagonists
*SURGICAL blood loss
*DISEASE complications
- Language
- ISSN
- 0952-8180
• Thrombotic complications became the Achilles heel of liver transplantation. • "Flat line" thromboelastogram tracing is predictive of intraoperative cardiovascular thrombosis. • DIC-like state with "flat line" tracing is not uncommon during liver transplantation • Intraoperative heparin thromboprophylaxis is efficacious, but underutilized. • Reversal of heparin may unleash an underlying DIC-like state. [ABSTRACT FROM AUTHOR]