Background and aims: Vulvovaginal candidiasis as a yeast infection is one of the most common reasons for women referring to clinics. Various causes could trigger this infection. It has been said in some studies that risk factor in predisposing vulvovaginal and in non predisposing vulvovaginal are different. The present study aimed to examine the relationship between predisposing factors and vulvovaginal candidiasis and the most prevalent symptoms. Methods: In this descriptive-analytical study, 140 people with the suspected diagnosis of recurrent vulvovaginal candidiasis were selected randomly. Two samples were selected from vaginal discharges for investigating the investigation the fungalk propable existence. A questionnaire including demographic and medical information was filled out. Factors such as pregnancy preventing method, material of clothes, cheesy discharges vaginal irritation, and erythema were assessed. The data were analyzed by SPSS software using chi-square and Fisher's exact test. Results: The mean age of the participants was 34.18±9.3 years. In the culture method, of the 140 vaginal samples, in the 46 cases (32.8%), candidiasis infections were grown. There was no significant relation between candidiasis infections and predisposing factors under study (P>0.05). There was a significant relation between candidiasis and clinical symptoms (cheesy discharge and vaginal erhythm) and clinical signs that the patients declared such as vaginal irritation and cheesy discharge (P<0.05) but there was no significant relation between itching and candidiasis infections (P>0.05). Conclusion: The results indicate that fewer then 33% of women with symptoms showed possible suffering of candidiasis infection, affliction to infection in their vaginal culture. Thus, it can't merely conclude about their candidiasis infection diagnosis based on some signs which patients declared them. [ABSTRACT FROM AUTHOR]