CD68-Positive Cells in Hepatic Angiomyolipoma.
- Resource Type
- Article
- Authors
- Tochio, Hitoshi; Tamaki, Eriko; Imai, Yukihiro; Iwasaki, Nobuhiro; Minowa, Kazushi; Chung, Hobyung; Suginoshita, Yoshiki; Inokuma, Tetsurou; Kudo, Masatoshi
- Source
- Oncology. 2017 Supplement 1, Vol. 92, p35-39. 5p.
- Subject
- *ANTIGEN analysis
*IMMUNOHISTOCHEMISTRY
*LIVER tumors
*RESEARCH methodology
*TISSUE culture
*ULTRASONIC imaging
*CONTRAST media
*DESCRIPTIVE statistics
*ANGIOMYOLIPOMA
- Language
- ISSN
- 0030-2414
Four resected specimens of hepatic angiomyolipoma in which uptake of Sonazoid was observed in the postvascular phase of Sonazoid-enhanced ultrasonography were analyzed. Macrophage localization in the tumor was revealed pathologically by immunohistochemical staining for CD68. CD68-positive cells were observed in the tumor in all cases. The density of CD68-positive cells was 100/mm 2 , and the ratio of CD68-positive cell density in the tumor to that in the surrounding parenchyma was 32-171%. These results suggested that the uptake of the contrast agent Sonazoid was related to the density of CD68-positive cells. [ABSTRACT FROM AUTHOR]