Oct4 shuffles Sox partners to direct cell fate.
- Resource Type
- Article
- Authors
- AlFatah Mansour, Abed; Hanna, Jacob H
- Source
- EMBO Journal. 4/3/2013, Vol. 32 Issue 7, p917-919. 3p. 1 Diagram.
- Subject
- *CELL differentiation
*MICROTUBULES
*CELL determination
*CELL division
*ADENOSINE triphosphatase
- Language
- ISSN
- 0261-4189
Early cell fate decisions demand rapid rewiring of transcriptional circuits. Stanton and colleagues report on enhancer‐dependent partnering of Oct4 with either Sox2 or Sox17 to switch from pluripotency to differentiation. [ABSTRACT FROM AUTHOR]