The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration.
- Resource Type
- Article
- Authors
- Mastrogiovanni, Marta; Vargas, Pablo; Rose, Thierry; Cuche, Céline; Esposito, Elric; Juzans, Marie; Laude, Hélène; Schneider, Amandine; Bernard, Mathilde; Goyard, Sophie; Renaudat, Charlotte; Ungeheuer, Marie-oëlle; Delon, Jérôme; Alcover, Andrés; Di Bartolo, Vincenzo
- Source
- Science Advances. 4/15/2022, Vol. 8 Issue 15, p1-12. 12p.
- Subject
- *ADENOMATOUS polyposis coli
*T cells
*FIBRONECTINS
*CYTOTOXIC T cells
*REGULATORY T cells
*MONONUCLEAR leukocytes
*TUMOR suppressor proteins
*LABORATORY management
- Language
- ISSN
- 2375-2548
The article presents a study which explores how tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration. It mentions that Adenomatous polyposis coli (APC) as a tumor suppressor whose mutations underlie familial adenomatous polyposis (FAP) and colorectal cancer. It discusses that APC importance in T cell biology.