After vaccination and the subsequent SARS-CoV-2 infection, the patient showed production of SARS-CoV-2-specific IgG antibodies against S1 and N viral proteins with high neutralization capacity. In order to interrogate the immunological response to COVID-19 vaccination and disease in our CD8-deficient patient, a blood sample was collected 15 days after the disease resolution and before receiving the 3rd vaccination dose. 1Magnitude of SARS-CoV-2-specific adaptive immune response in a CD8 immunodeficient patient and controls following SARS-CoV-2 vaccination and infection. [Extracted from the article]