Autism: Comorbidities and Treatment Patterns in the Real World, a Retrospective Cohort Study Among Children, Adolescents and Adults Newly Diagnosed with Autism.
- Resource Type
- Article
- Authors
- Shoaib, Azza, ; Cepeda, M. Soledad; Murray, Gayle; Ochs-Ross, Rachel
- Source
- Journal of Autism & Developmental Disorders; Oct2022, Vol. 52 Issue 10, p4311-4320, 10p, 1 Diagram, 5 Charts
- Subject
- Retrospective studies
Behavior therapy
Attention-deficit hyperactivity disorder
Affective disorders
Autism
Longitudinal method
Children
Adolescence
Diagnosis of autism
Treatment of autism
Databases
Medical information storage & retrieval systems
Descriptive statistics
Combined modality therapy
Comorbidity
Disease complications
United States
- Language
- ISSN
- 01623257
We used real world data to summarize comorbidities and interventions among patients newly diagnosed with autism spectrum disorder (ASD). Data were derived from two claims-based US healthcare databases; Medicaid and Optum to construct a retrospective cohort of 36,000 patients. Attention-Deficit-Hyperactivity-Disorder (ADHD) was the most common co-morbidity (Medicaid: 50.09%; Optum: 44.16%), followed by mood disorder (Medicaid: 16.56% and Optum: 17.47%). Most patients received at least one type of treatment. Behavioral therapy was common (74.64% in Medicaid and 71.97% in Optum). More than half the cohorts received at least 1 pharmacotherapy. However, pharmacotherapies were diverse. Combination therapy and therapy switching was common. Understanding the clinical diversity and complexity of patients with ASD is an important first step in understanding unmet therapeutic needs. [ABSTRACT FROM AUTHOR]