Research progress of targeted therapy combined with immunotherapy for hepatocellular carcinoma
- Resource Type
- article
- Authors
- Shuqi Xie; Mengchao Wang; Chuanxiu Zeng; Yan Ou; Lu Zhao; Dong Wang; Liwei Chen; Fanming Kong; Dan Yi
- Source
- Frontiers in Oncology, Vol 13 (2023)
- Subject
- targeted therapy
immunotherapy
research progress
hepatocellular carcinoma
combination therapy
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
- Language
- English
- ISSN
- 2234-943X
Hepatocellular carcinoma is a common gastrointestinal malignancy with a high mortality rate and limited treatment options. Molecularly targeted drugs combined with immune checkpoint inhibitors have shown unique advantages over single-agent applications, significantly prolonging patient survival. This paper reviews the research progress of molecular-targeted drugs combined with immune checkpoint inhibitors in the treatment of hepatocellular carcinoma and discusses the effectiveness and safety of the combination of the two drugs to provide a reference for the further application of molecular-targeted drugs combined with immune checkpoint inhibitors in clinical practice.