Prophylactic ligation of uterine arteries at its origin in laparoscopic surgical staging for endometrial cancer
- Resource Type
- Authors
- Ali Yavuzcan; Kadir Bakay
- Source
- The journal of obstetrics and gynaecology researchReferences. 47(12)
- Subject
- medicine.medical_specialty
Pelvic Lymphadenectomy
Surgical staging
Hysterectomy
laparoscopic
transperitoneal lymphadenectomy
medicine.artery
Statistical significance
medicine
Humans
ligation
Uterine artery
Lymph node
Lymph-Node Count
Neoplasm Staging
Retrospective Studies
Laparotomy
business.industry
Endometrial cancer
Carcinoma
Obstetrics and Gynecology
Positive Pelvic Lymph Node
Retrospective cohort study
medicine.disease
Surgery
Endometrial Neoplasms
Uterine Artery
medicine.anatomical_structure
endometrial cancer
Lymph Node Excision
Female
Laparoscopy
Ligation
business
- Language
- ISSN
- 1447-0756
Aim The aim of this study was to compare the surgical outcomes between patients who were staged laparoscopically for early-stage endometrioid-type endometrial cancer (EC) between those who underwent prophylactic ligation of uterine arteries (UAs) prior to pelvic lymphadenectomy and the patients who were operated with standard procedure. Methods This retrospective study was conducted in women diagnosed with early-stage and low/intermediate-risk endometrioid-type EC. The control group included patients who underwent standard laparoscopic pelvic lymphadenectomy and the study group concerned patients who underwent prophylactic ligation of UA prior to pelvic lymphadenectomy. The prophylactic ligation of UA procedure was performed at a point just proximal to its origin. Results The mean lymph node count dissected in the study group was higher in terms of statistical significance (17.5 +/- 2.2 vs. 19.8 +/- 3.6, p = 0.003 and p < 0.05). The rate of the patients who had a positive pelvic lymph node detected did not differ between groups (7.4% vs. 16.7%, p = 0.258 and p < 0.05). The operation time (OT) of the patients in the study group did not differ between groups (p = 0.546 and p < 0.05). Hemoglobin drop (-0.5 +/- 0.7) and hematocrite drop (-0.8 +/- 0.9) values in the study group were found to be lower in the study group (p = 0.000, p = 0.000, and p < 0.05). Conclusions Performing prophylactic ligation of UA at its origin prevents unwanted bleeding and facilitates the laparoscopic pelvic lymphadenectomy procedure. WOS:000700243300001 2-s2.0-85115674696 PubMed: 34571568