The paper describes an approach to the documentation of scientific data produced in heritage sciences interdisciplinary research. Since such activities fall within the scope of a scientific discipline (e.g. physics or chemistry) and of cultural heritage, the documentation system must draw from both. The paper proposes an overarching system based on the use of CIDOC CRM and its extensions CRMsci, CRMdig and CRMpe to model physical and digital objects, events and activities, and actors, i.e. people and teams. It is suggested that such a model could address most – if not all – of the issues encountered documenting heritage sciences results. The use of the CRM provides straightforward connection and interoperability with the general documentation of cultural heritage and thus tightly links scientific analyses to their heritage context. A number of examples demonstrate how to apply this approach to different cases and offer an overview of the whole model, which is not fully exposed here: full details will be given in a separate technical document.