Alzheimer's disease (AD) is the most prevalent form of dementia among the aging population. Cumulative studies aim to find non-invasive biomarkers in the early stages of AD. Saliva can be obtained easily, and salivary biomarkers have been proven effective in detecting neurodegenerative diseases. To find effective biomarkers in saliva and to help the diagnosis of AD, we performed a meta-analysis focusing on the salivary biomarkers (β-amyloid 1-42 (AβWe conducted a systematic online search for eligible studies reporting data on salivary biomarkers reflecting AβA total of thirteen studies were included in the meta-analysis, of them seven involved salivary AβThe pooled results provide evidence that salivary Aβ