A key moment of the diagnostic phase, prior to the restoration project, is the morphological and chemical characterization of historical grouts. This analysis is essential when it's necessary carry brickwork's restoration actions of conservative nature on an architectural work. The current trend, relating to the choice of the grouts to be applied during restoration operations, is more and more one which the designers rely on the commercial products presented as "suitable" for different applications on historical structures, as well as able to guarantee specific performances for all eventualities. Today, therefore, the designers unlikely deepen the study of grouts to adopt and this doesn't make them fully aware of their characteristics, their chemical compositions as well as the level of compatibility with the historical material on which they will apply and with which they will interact. And this shallowness often leads to situations of premature structural deteriorations due to the application of not suitable products for the native materials or for the environmental conditions to which they are exposed. In this case it's suggested a study on the characterization of historical grouts through the SEM/EDX microscopic analysis to characterize the former Jesuit college of Amantea (Cs). The characterization of the grouts carried out on this structure, stands as an essential moment of the restoration process underway on this important architecture.