Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance)
- Resource Type
- Authors
- Kroetz, Deanna; Witte, John; Chhibber, A; Mefford, J; Stahl, EA; Pendergrass, SA; Baldwin, RM; Owzar, K; Li, M; Winer, EP; Hudis, CA; Zembutsu, H
- Source
- Kroetz, Deanna; Witte, John; Chhibber, A; Mefford, J; Stahl, EA; Pendergrass, SA; et al.(2014). Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance). UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2qt5z099
- Subject
- Language
- English
Peripheral neuropathy is a common dose-limiting toxicity for patients treated with paclitaxel. For most individuals, there are no known risk factors that predispose patients to the adverse event, and pathogenesis for paclitaxel-induced peripheral neuropath