The article discusses medical research. F. Caglayan and associates investigated the possible use of D-lactate as a predictor in the diagnosis of appendicitis. Based on their data, venous D-lactate, which had the lowest false- negative rate among the laboratory parameters, may be a useful diagnostic marker for appendicitis. They concluded that neither D-lactate level, nor C-reactive protein, nor white blood cell (WBC) counts were helpful in identifying the type of the appendicitis. A recent clinical study, aimed to determine the value and the utility of plasma D-lactate level in distinguishing perforated from acute nonperforated appendicitis in children.