This letter published in the journal Leukemia & Lymphoma discusses a study on AA-type amyloidosis associated with lymphoma. The study includes case reports of five patients with AA-type amyloidosis associated with lymphoma, detailing their medical histories, diagnoses, and outcomes. The study highlights the need for further research on this rare but possible association and its prognosis. A literature review identified thirteen articles reporting on fourteen patients with AA amyloidosis associated with lymphoma, providing information on demographics, comorbidities, lymphoma characteristics, AAA diagnosis circumstances, and treatment outcomes. The study found that AAA could complicate both Hodgkin lymphoma and non-Hodgkin lymphoma of various histological types, with renal involvement being the most common presentation. The mortality rate was high, primarily due to septic complications. The article recommends prompt and targeted treatment for AAA in lymphoma patients, as well as infection prophylaxis. [Extracted from the article]